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Modeling Haplotype-Haplotype Interactions in Case-Control Genetic Association Studies

Haplotype analysis has been increasingly used to study the genetic basis of human diseases, but models for characterizing genetic interactions between haplotypes from different chromosomal regions have not been well developed in the current literature. In this article, we describe a statistical mode...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Liu, Ruitao, Wang, Zhong, Culver, Daniel A., Wu, Rongling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260479/
https://www.ncbi.nlm.nih.gov/pubmed/22303409
http://dx.doi.org/10.3389/fgene.2012.00002