Cargando…

ZBTB1 is a determinant of lymphoid development

In this study, we describe a chemically induced mouse mutation that caused a complete and cell-intrinsic T cell deficiency. Development of other lymphoid lineages was also partially impaired and was severely compromised under competitive conditions. Positional cloning, retroviral transduction, and a...

Descripción completa

Detalles Bibliográficos
Autores principales: Siggs, Owen M., Li, Xiaohong, Xia, Yu, Beutler, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260866/
https://www.ncbi.nlm.nih.gov/pubmed/22201126
http://dx.doi.org/10.1084/jem.20112084