A novel neuroprotective therapy for Parkinson’s disease using a viral noncoding RNA that protects mitochondrial Complex I activity

Parkinson’s disease (PD) is a neurodegenerative disorder that results in the loss of nigrostriatal dopamine neurons. The etiology of this cell loss is unknown, but it involves abnormalities in mitochondrial function. In this study, we have demonstrated that the administration of a novel noncoding p1...

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Detalles Bibliográficos
Autores principales: Kuan, Wei-Li, Poole, Emma, Fletcher, Michael, Karniely, Sharon, Tyers, Pam, Wills, Mark, Barker, Roger A., Sinclair, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260871/
https://www.ncbi.nlm.nih.gov/pubmed/22184634
http://dx.doi.org/10.1084/jem.20111126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260871/
https://www.ncbi.nlm.nih.gov/pubmed/22184634
http://dx.doi.org/10.1084/jem.20111126

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