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A novel neuroprotective therapy for Parkinson’s disease using a viral noncoding RNA that protects mitochondrial Complex I activity
Parkinson’s disease (PD) is a neurodegenerative disorder that results in the loss of nigrostriatal dopamine neurons. The etiology of this cell loss is unknown, but it involves abnormalities in mitochondrial function. In this study, we have demonstrated that the administration of a novel noncoding p1...
Autores principales: | Kuan, Wei-Li, Poole, Emma, Fletcher, Michael, Karniely, Sharon, Tyers, Pam, Wills, Mark, Barker, Roger A., Sinclair, John H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260871/ https://www.ncbi.nlm.nih.gov/pubmed/22184634 http://dx.doi.org/10.1084/jem.20111126 |
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