Structural Analysis and Stochastic Modelling Suggest a Mechanism for Calmodulin Trapping by CaMKII

Activation of CaMKII by calmodulin and the subsequent maintenance of constitutive activity through autophosphorylation at threonine residue 286 (Thr286) are thought to play a major role in synaptic plasticity. One of the effects of autophosphorylation at Thr286 is to increase the apparent affinity o...

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Detalles Bibliográficos
Autores principales: Stefan, Melanie I., Marshall, David P., Le Novère, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261145/
https://www.ncbi.nlm.nih.gov/pubmed/22279535
http://dx.doi.org/10.1371/journal.pone.0029406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261145/
https://www.ncbi.nlm.nih.gov/pubmed/22279535
http://dx.doi.org/10.1371/journal.pone.0029406

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