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OTUB1 Overexpression in Mesangial Cells Is a Novel Regulator in the Pathogenesis of Glomerulonephritis through the Decrease of DCN Level

BACKGROUND: OTUB1 is a member of OTUs (Ovarian-tumor-domain-containing proteases), a deubiquitinating enzymes family (DUBs), which was shown as a proteasome-associated DUB to be involved in the proteins Ub-dependent degradation. It has been reported that OTUB1 was expressed in kidney tissue. But its...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Hu, Ruimin, Wu, Huijuan, Jiang, Weina, Sun, Yu, Wang, Yan, Song, Yanan, Jin, Tong, Zhang, Hongxia, Mao, Xin, Zhao, Zhonghua, Zhang, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261153/
https://www.ncbi.nlm.nih.gov/pubmed/22279542
http://dx.doi.org/10.1371/journal.pone.0029654