TLR5 Risk-Associated Haplotype for Canine Inflammatory Bowel Disease Confers Hyper-Responsiveness to Flagellin

Single nucleotide polymorphisms (SNP) in the TLR5 gene have been associated with human inflammatory bowel disease (IBD) and animal models of this disease. We recently demonstrated a significant association between three non-synonymous SNPs in the canine TLR5 gene and IBD in German shepherd dogs (GSD...

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Detalles Bibliográficos
Autores principales: Kathrani, Aarti, Holder, Angela, Catchpole, Brian, Alvarez, Lorena, Simpson, Kenneth, Werling, Dirk, Allenspach, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261174/
https://www.ncbi.nlm.nih.gov/pubmed/22279566
http://dx.doi.org/10.1371/journal.pone.0030117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261174/
https://www.ncbi.nlm.nih.gov/pubmed/22279566
http://dx.doi.org/10.1371/journal.pone.0030117

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