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Circulating Angiopoietin-2 as a Biomarker in ANCA-Associated Vasculitis

The endothelial-specific Angiopoietin-Tie2 ligand-receptor system is an important regulator of endothelial activation. Binding of angiopoietin-2 (Ang-2) to Tie2 receptor renders the endothelial barrier responsive to pro-inflammatory cytokines. We previously showed that circulating Ang-2 correlated w...

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Detalles Bibliográficos
Autores principales: Monach, Paul A., Kümpers, Philipp, Lukasz, Alexander, Tomasson, Gunnar, Specks, Ulrich, Stone, John H., Cuthbertson, David, Krischer, Jeffrey, Carette, Simon, Ding, Linna, Hoffman, Gary S., Iklé, David, Kallenberg, Cees G. M., Khalidi, Nader A., Langford, Carol A., Seo, Philip, St. Clair, E. William, Spiera, Robert, Tchao, Nadia, Ytterberg, Steven R., Haubitz, Marion, Merkel, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261176/
https://www.ncbi.nlm.nih.gov/pubmed/22279570
http://dx.doi.org/10.1371/journal.pone.0030197