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Modelling of Mouse Experimental Colitis by Global Property Screens: A Holistic Approach to Assess Drug Effects in Inflammatory Bowel Disease

Preclinical disease models play an important role in the establishment of new treatment paradigms, identification of biomarkers and assessment of drug efficacy and safety. However, the accuracy of these models in context of the human disease are sometimes questioned, e.g. due to trials failing to co...

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Detalles Bibliográficos
Autores principales: Gottfries, Johan, Melgar, Silvia, Michaëlsson, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261178/
https://www.ncbi.nlm.nih.gov/pubmed/22279558
http://dx.doi.org/10.1371/journal.pone.0030005