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Modelling of Mouse Experimental Colitis by Global Property Screens: A Holistic Approach to Assess Drug Effects in Inflammatory Bowel Disease
Preclinical disease models play an important role in the establishment of new treatment paradigms, identification of biomarkers and assessment of drug efficacy and safety. However, the accuracy of these models in context of the human disease are sometimes questioned, e.g. due to trials failing to co...
Autores principales: | Gottfries, Johan, Melgar, Silvia, Michaëlsson, Erik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261178/ https://www.ncbi.nlm.nih.gov/pubmed/22279558 http://dx.doi.org/10.1371/journal.pone.0030005 |
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