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Sequence Coevolution between RNA and Protein Characterized by Mutual Information between Residue Triplets

Coevolving residues in a multiple sequence alignment provide evolutionary clues of biophysical interactions in 3D structure. Despite a rich literature describing amino acid coevolution within or between proteins and nucleic acid coevolution within RNA, to date there has been no direct evidence of co...

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Detalles Bibliográficos
Autores principales: Brandman, Relly, Brandman, Yigal, Pande, Vijay S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261191/
https://www.ncbi.nlm.nih.gov/pubmed/22279560
http://dx.doi.org/10.1371/journal.pone.0030022