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Sequence Coevolution between RNA and Protein Characterized by Mutual Information between Residue Triplets
Coevolving residues in a multiple sequence alignment provide evolutionary clues of biophysical interactions in 3D structure. Despite a rich literature describing amino acid coevolution within or between proteins and nucleic acid coevolution within RNA, to date there has been no direct evidence of co...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261191/ https://www.ncbi.nlm.nih.gov/pubmed/22279560 http://dx.doi.org/10.1371/journal.pone.0030022 |