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ErbB2, EphrinB1, Src Kinase and PTPN13 Signaling Complex Regulates MAP Kinase Signaling in Human Cancers

In non-cancerous cells, phosphorylated proteins exist transiently, becoming de-phosphorylated by specific phosphatases that terminate propagation of signaling pathways. In cancers, compromised phosphatase activity and/or expression occur and contribute to tumor phenotype. The non-receptor phosphatas...

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Detalles Bibliográficos
Autores principales: Vermeer, Paola D., Bell, Megan, Lee, Kimberly, Vermeer, Daniel W., Wieking, Byrant G., Bilal, Erhan, Bhanot, Gyan, Drapkin, Ronny I., Ganesan, Shridar, Klingelhutz, Aloysius J., Hendriks, Wiljan J., Lee, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261204/
https://www.ncbi.nlm.nih.gov/pubmed/22279592
http://dx.doi.org/10.1371/journal.pone.0030447