Mitochondrial Oxidative Stress due to Complex I Dysfunction Promotes Fibroblast Activation and Melanoma Cell Invasiveness

Increased ROS (cellular reactive oxygen species) are characteristic of both fibrosis and tumour development. ROS induce the trans-differentiation to myofibroblasts, the activated form of fibroblasts able to promote cancer progression. Here, we report the role of ROS produced in response to dysfuncti...

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Detalles Bibliográficos
Autores principales: Taddei, Maria Letizia, Giannoni, Elisa, Raugei, Giovanni, Scacco, Salvatore, Sardanelli, Anna Maria, Papa, Sergio, Chiarugi, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261495/
https://www.ncbi.nlm.nih.gov/pubmed/22272371
http://dx.doi.org/10.1155/2012/684592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261495/
https://www.ncbi.nlm.nih.gov/pubmed/22272371
http://dx.doi.org/10.1155/2012/684592

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