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Mitochondrial Oxidative Stress due to Complex I Dysfunction Promotes Fibroblast Activation and Melanoma Cell Invasiveness

Increased ROS (cellular reactive oxygen species) are characteristic of both fibrosis and tumour development. ROS induce the trans-differentiation to myofibroblasts, the activated form of fibroblasts able to promote cancer progression. Here, we report the role of ROS produced in response to dysfuncti...

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Detalles Bibliográficos
Autores principales:	Taddei, Maria Letizia, Giannoni, Elisa, Raugei, Giovanni, Scacco, Salvatore, Sardanelli, Anna Maria, Papa, Sergio, Chiarugi, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261495/ https://www.ncbi.nlm.nih.gov/pubmed/22272371 http://dx.doi.org/10.1155/2012/684592

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