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FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors

The transcription factors that control lineage specification of haematopoietic stem cells (HSCs) have been well described for the myeloid and lymphoid lineages, whereas transcriptional control of erythroid (E) and megakaryocytic (Mk) fate is less understood. We here use conditional removal of the GA...

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Detalles Bibliográficos
Autores principales: Mancini, Elena, Sanjuan-Pla, Alejandra, Luciani, Luisa, Moore, Susan, Grover, Amit, Zay, Agnes, Rasmussen, Kasper D, Luc, Sidinh, Bilbao, Daniel, O'Carroll, Donal, Jacobsen, Sten Eirik, Nerlov, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261555/
https://www.ncbi.nlm.nih.gov/pubmed/22068055
http://dx.doi.org/10.1038/emboj.2011.390