The proline TP53 variant stimulates likely lymphangiogenesis in an orthotopic mouse model of pancreatic cancer

BACKGROUND: Pancreatic cancer is a deadly disease characterised by high incidence of TP53 mutations. Restoration of TP53 function is perceived as a highly attractive therapeutic strategy, whose effects are not well characterised. METHODS: The current work adapted an inducible strategy of stage-speci...

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Detalles Bibliográficos
Autores principales: Otto, N, Schulz, P, Scholz, A, Hauff, P, Schlegelberger, B, Detjen, K M, Wiedenmann, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261666/
https://www.ncbi.nlm.nih.gov/pubmed/22146521
http://dx.doi.org/10.1038/bjc.2011.521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261666/
https://www.ncbi.nlm.nih.gov/pubmed/22146521
http://dx.doi.org/10.1038/bjc.2011.521

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