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The proline TP53 variant stimulates likely lymphangiogenesis in an orthotopic mouse model of pancreatic cancer
BACKGROUND: Pancreatic cancer is a deadly disease characterised by high incidence of TP53 mutations. Restoration of TP53 function is perceived as a highly attractive therapeutic strategy, whose effects are not well characterised. METHODS: The current work adapted an inducible strategy of stage-speci...
Autores principales: | Otto, N, Schulz, P, Scholz, A, Hauff, P, Schlegelberger, B, Detjen, K M, Wiedenmann, B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261666/ https://www.ncbi.nlm.nih.gov/pubmed/22146521 http://dx.doi.org/10.1038/bjc.2011.521 |
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