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Systematic exploration of synergistic drug pairs

Drug synergy allows a therapeutic effect to be achieved with lower doses of component drugs. Drug synergy can result when drugs target the products of genes that act in parallel pathways (‘specific synergy’). Such cases of drug synergy should tend to correspond to synergistic genetic interaction bet...

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Detalles Bibliográficos
Autores principales: Cokol, Murat, Chua, Hon Nian, Tasan, Murat, Mutlu, Beste, Weinstein, Zohar B, Suzuki, Yo, Nergiz, Mehmet E, Costanzo, Michael, Baryshnikova, Anastasia, Giaever, Guri, Nislow, Corey, Myers, Chad L, Andrews, Brenda J, Boone, Charles, Roth, Frederick P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261710/
https://www.ncbi.nlm.nih.gov/pubmed/22068327
http://dx.doi.org/10.1038/msb.2011.71