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Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome

Genetic analysis in Drosophila melanogaster has been widely used to identify a system of genes that control cell growth in response to insulin and nutrients. Many of these genes encode components of the insulin receptor/target of rapamycin (InR/TOR) pathway. However, the biochemical context of this...

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Detalles Bibliográficos
Autores principales: Glatter, Timo, Schittenhelm, Ralf B, Rinner, Oliver, Roguska, Katarzyna, Wepf, Alexander, Jünger, Martin A, Köhler, Katja, Jevtov, Irena, Choi, Hyungwon, Schmidt, Alexander, Nesvizhskii, Alexey I, Stocker, Hugo, Hafen, Ernst, Aebersold, Ruedi, Gstaiger, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261712/
https://www.ncbi.nlm.nih.gov/pubmed/22068330
http://dx.doi.org/10.1038/msb.2011.79