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Deep proteome and transcriptome mapping of a human cancer cell line

While the number and identity of proteins expressed in a single human cell type is currently unknown, this fundamental question can be addressed by advanced mass spectrometry (MS)-based proteomics. Online liquid chromatography coupled to high-resolution MS and MS/MS yielded 166 420 peptides with uni...

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Detalles Bibliográficos
Autores principales: Nagaraj, Nagarjuna, Wisniewski, Jacek R, Geiger, Tamar, Cox, Juergen, Kircher, Martin, Kelso, Janet, Pääbo, Svante, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261714/
https://www.ncbi.nlm.nih.gov/pubmed/22068331
http://dx.doi.org/10.1038/msb.2011.81