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Estrogen Receptor-Alpha 36 Mediates Mitogenic Antiestrogen Signaling in ER-Negative Breast Cancer Cells

It is prevailingly thought that the antiestrogens tamoxifen and ICI 182, 780 are competitive antagonists of the estrogen-binding site of the estrogen receptor-alpha (ER-α). However, a plethora of evidence demonstrated both antiestrogens exhibit agonist activities in different systems such as activat...

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Detalles Bibliográficos
Autores principales: Zhang, XinTian, Ding, Ling, Kang, LianGuo, Wang, Zhao-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261853/
https://www.ncbi.nlm.nih.gov/pubmed/22276155
http://dx.doi.org/10.1371/journal.pone.0030174