Autocrine Prostaglandin E(2) Signaling Promotes Tumor Cell Survival and Proliferation in Childhood Neuroblastoma

BACKGROUND: Prostaglandin E(2) (PGE(2)) is an important mediator in tumor-promoting inflammation. High expression of cyclooxygenase-2 (COX-2) has been detected in the embryonic childhood tumor neuroblastoma, and treatment with COX inhibitors significantly reduces tumor growth. Here, we have investig...

Descripción completa

Detalles Bibliográficos
Autores principales: Rasmuson, Agnes, Kock, Anna, Fuskevåg, Ole Martin, Kruspig, Björn, Simón-Santamaría, Jaione, Gogvadze, Vladimir, Johnsen, John Inge, Kogner, Per, Sveinbjörnsson, Baldur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261878/
https://www.ncbi.nlm.nih.gov/pubmed/22276108
http://dx.doi.org/10.1371/journal.pone.0029331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261878/
https://www.ncbi.nlm.nih.gov/pubmed/22276108
http://dx.doi.org/10.1371/journal.pone.0029331

Ejemplares similares