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Stem Cells Propagate Their DNA by Random Segregation in the Flatworm Macrostomum lignano

Adult stem cells are proposed to have acquired special features to prevent an accumulation of DNA-replication errors. Two such mechanisms, frequently suggested to serve this goal are cellular quiescence, and non-random segregation of DNA strands during stem cell division, a theory designated as the...

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Detalles Bibliográficos
Autores principales: Verdoodt, Freija, Willems, Maxime, Mouton, Stijn, De Mulder, Katrien, Bert, Wim, Houthoofd, Wouter, Smith, Julian, Ladurner, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261893/
https://www.ncbi.nlm.nih.gov/pubmed/22276162
http://dx.doi.org/10.1371/journal.pone.0030227