Amyloid Precursor Protein and Proinflammatory Changes Are Regulated in Brain and Adipose Tissue in a Murine Model of High Fat Diet-Induced Obesity

BACKGROUND: Middle age obesity is recognized as a risk factor for Alzheimer's disease (AD) although a mechanistic linkage remains unclear. Based upon the fact that obese adipose tissue and AD brains are both areas of proinflammatory change, a possible common event is chronic inflammation. Since...

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Detalles Bibliográficos
Autores principales: Puig, Kendra L., Floden, Angela M., Adhikari, Ramchandra, Golovko, Mikhail Y., Combs, Colin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261903/
https://www.ncbi.nlm.nih.gov/pubmed/22276186
http://dx.doi.org/10.1371/journal.pone.0030378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261903/
https://www.ncbi.nlm.nih.gov/pubmed/22276186
http://dx.doi.org/10.1371/journal.pone.0030378

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