Cargando…

Amyloid Precursor Protein and Proinflammatory Changes Are Regulated in Brain and Adipose Tissue in a Murine Model of High Fat Diet-Induced Obesity

BACKGROUND: Middle age obesity is recognized as a risk factor for Alzheimer's disease (AD) although a mechanistic linkage remains unclear. Based upon the fact that obese adipose tissue and AD brains are both areas of proinflammatory change, a possible common event is chronic inflammation. Since...

Descripción completa

Detalles Bibliográficos
Autores principales:	Puig, Kendra L., Floden, Angela M., Adhikari, Ramchandra, Golovko, Mikhail Y., Combs, Colin K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261903/ https://www.ncbi.nlm.nih.gov/pubmed/22276186 http://dx.doi.org/10.1371/journal.pone.0030378

Ejemplares similares

Amyloid precursor protein modulates macrophage phenotype and diet-dependent weight gain
por: Puig, Kendra L., et al.
Publicado: (2017)

Amyloid Precursor Protein Mediated Changes in Intestinal Epithelial Phenotype In Vitro
por: Puig, Kendra L., et al.
Publicado: (2015)

Defining the contribution of neuroinflammation to Parkinson’s disease in humanized immune system mice
por: Manocha, Gunjan Dhawan, et al.
Publicado: (2017)

Liver Bile Acid Changes in Mouse Models of Alzheimer’s Disease
por: Kaur, Harpreet, et al.
Publicado: (2021)

Dysregulation of Amyloid Precursor Protein Impairs Adipose Tissue Mitochondrial Function and Promotes Obesity
por: An, Yu A., et al.
Publicado: (2019)

Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer’s disease
por: Dhawan, Gunjan, et al.
Publicado: (2012)

Continuation of Exercise Is Necessary to Inhibit High Fat Diet-Induced β-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic Mice
por: Maesako, Masato, et al.
Publicado: (2013)

TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes
por: Eckfeld, Celina, et al.
Publicado: (2023)

Sex-Specific Effect of High-Fat Diet on Glycerol Metabolism in Murine Adipose Tissue and Liver
por: Iena, Francesco Maria, et al.
Publicado: (2020)

CD226 knockout alleviates high-fat diet induced obesity by suppressing proinflammatory macrophage phenotype
por: Ma, Jingchang, et al.
Publicado: (2021)

Proinflammatory Cytokines in Prostate Cancer Development and Progression Promoted by High-Fat Diet
por: Xu, Hua, et al.
Publicado: (2015)

Attenuation of microglial activation in a mouse model of Alzheimer’s disease via NFAT inhibition
por: Rojanathammanee, Lalida, et al.
Publicado: (2015)

Amyloid precursor protein and amyloid precursor-like protein 2 in cancer
por: Pandey, Poomy, et al.
Publicado: (2016)

The amyloid precursor protein: beyond amyloid
por: Zheng, Hui, et al.
Publicado: (2006)

High fat diet-induced obesity leads to proinflammatory response associated with higher expression of NOD2 protein
por: Kim, Min Soo, et al.
Publicado: (2011)

Hyperuricemia as a Mediator of the Proinflammatory Endocrine Imbalance in the Adipose Tissue in a Murine Model of the Metabolic Syndrome
por: Baldwin, William, et al.
Publicado: (2011)

Anti-α4β1 Integrin Antibodies Attenuated Brain Inflammatory Changes in a Mouse Model of Alzheimer’s Disease
por: Manocha, Gunjan, et al.
Publicado: (2018)

Single garlic oil modulates T cells activation and proinflammatory cytokine in mice with high fat diet
por: Lestari, Sri Rahayu, et al.
Publicado: (2020)

Overexpression of the Gene Encoding Neurosecretory Protein GL Precursor Prevents Excessive Fat Accumulation in the Adipose Tissue of Mice Fed a Long-Term High-Fat Diet
por: Fukumura, Keisuke, et al.
Publicado: (2021)

IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer’s Disease Transgenic Mouse Model
por: Sohrabi, Mona, et al.
Publicado: (2020)

Antibiotic perturbation of the murine gut microbiome enhances the adiposity, insulin resistance, and liver disease associated with high-fat diet
por: Mahana, Douglas, et al.
Publicado: (2016)

The Role of Prenatal Psychosocial Stress in the Associations of a Proinflammatory Diet in Pregnancy With Child Adiposity and Growth Trajectories
por: Monthé-Drèze, Carmen, et al.
Publicado: (2023)

Amyloid precursor protein modulates β-catenin degradation
por: Chen, Yuzhi, et al.
Publicado: (2007)

Interactions between amyloid, amyloid precursor protein, and mitochondria
por: Wilkins, Heather M.
Publicado: (2023)

Mutant Amyloid Precursor Protein Differentially Alters Adipose Biology under Obesogenic and Non-Obesogenic Conditions
por: Freeman, Linnea R., et al.
Publicado: (2012)

Adhesion of monocytes to type I collagen stimulates an APP-dependent proinflammatory signaling response and release of Aβ1-40
por: Sondag, Cindy M, et al.
Publicado: (2010)

Deletion of Serum Amyloid A3 Improves High Fat High Sucrose Diet-Induced Adipose Tissue Inflammation and Hyperlipidemia in Female Mice
por: den Hartigh, Laura J., et al.
Publicado: (2014)

Biology and pathophysiology of the amyloid precursor protein
por: Zheng, Hui, et al.
Publicado: (2011)

Amyloid Precursor Protein and Alzheimer’s Disease
por: Orobets, Kseniia S., et al.
Publicado: (2023)

Elevated levels of proinflammatory volatile metabolites in feces of high fat diet fed KK-A(y) mice
por: Uchikawa, Misaki, et al.
Publicado: (2020)

Whole Cigarette Smoke Condensates Induce Accumulation of Amyloid Beta Precursor Protein with Oxidative Stress in Murine Astrocytes
por: Park, Eun-Jung, et al.
Publicado: (2021)

Cafeteria diet increased adiposity in comparison to high fat diet in young male rats
por: Buyukdere, Yucel, et al.
Publicado: (2019)

Cinchonine Prevents High-Fat-Diet-Induced Obesity through Downregulation of Adipogenesis and Adipose Inflammation
por: Jung, Sung A., et al.
Publicado: (2012)

Improvement of Adipose Macrophage Polarization in High Fat Diet-Induced Obese GHSR Knockout Mice
por: Yuan, Fang, et al.
Publicado: (2018)

Celastrol prevents high‐fat diet‐induced obesity by promoting white adipose tissue browning
por: Wang, Bingwei, et al.
Publicado: (2021)

Reduction of obesity and hepatic adiposity in high-fat diet-induced rats by besunyen slimming tea
por: Yu, Chingwen, et al.
Publicado: (2023)

Mentha canadensis attenuates adiposity and hepatic steatosis in high-fat diet-induced obese mice
por: Han, Youngji, et al.
Publicado: (2023)

Inhibitory Effects of Trifluoperazine on Peripheral Proinflammatory Cytokine Expression and Hypothalamic Microglia Activation in Obese Mice Induced by Chronic Feeding With High-Fat-Diet
por: Huang, Hui-Ting, et al.
Publicado: (2021)

High Fat Diet Accelerates Pathogenesis of Murine Crohn’s Disease-Like Ileitis Independently of Obesity
por: Gruber, Lisa, et al.
Publicado: (2013)

6-Gingerol Ameliorates Adiposity and Inflammation in Adipose Tissue in High Fat Diet-Induced Obese Mice: Association with Regulating of Adipokines
por: Hong, Kyung Hee, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_eu77ac6abcehn8bj7hr3r662ng