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Senescent Cells in Growing Tumors: Population Dynamics and Cancer Stem Cells
Tumors are defined by their intense proliferation, but sometimes cancer cells turn senescent and stop replicating. In the stochastic cancer model in which all cells are tumorigenic, senescence is seen as the result of random mutations, suggesting that it could represent a barrier to tumor growth. In...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261911/ https://www.ncbi.nlm.nih.gov/pubmed/22275856 http://dx.doi.org/10.1371/journal.pcbi.1002316 |