Cargando…
Cohesin Protects Genes against γH2AX Induced by DNA Double-Strand Breaks
Chromatin undergoes major remodeling around DNA double-strand breaks (DSB) to promote repair and DNA damage response (DDR) activation. We recently reported a high-resolution map of γH2AX around multiple breaks on the human genome, using a new cell-based DSB inducible system. In an attempt to further...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261922/ https://www.ncbi.nlm.nih.gov/pubmed/22275873 http://dx.doi.org/10.1371/journal.pgen.1002460 |