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Cohesin Protects Genes against γH2AX Induced by DNA Double-Strand Breaks
Chromatin undergoes major remodeling around DNA double-strand breaks (DSB) to promote repair and DNA damage response (DDR) activation. We recently reported a high-resolution map of γH2AX around multiple breaks on the human genome, using a new cell-based DSB inducible system. In an attempt to further...
Autores principales: | Caron, Pierre, Aymard, Francois, Iacovoni, Jason S., Briois, Sébastien, Canitrot, Yvan, Bugler, Beatrix, Massip, Laurent, Losada, Ana, Legube, Gaëlle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261922/ https://www.ncbi.nlm.nih.gov/pubmed/22275873 http://dx.doi.org/10.1371/journal.pgen.1002460 |
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