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A Signal-to-Noise Crossover Dose as the Point of Departure for Health Risk Assessment

Background: The U.S. National Toxicology Program (NTP) cancer bioassay database provides an opportunity to compare both existing and new approaches to determining points of departure (PoDs) for establishing reference doses (RfDs). Objectives: The aims of this study were a) to investigate the risk as...

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Detalles Bibliográficos
Autores principales: Sand, Salomon, Portier, Christopher J., Krewski, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261975/
https://www.ncbi.nlm.nih.gov/pubmed/21813365
http://dx.doi.org/10.1289/ehp.1003327