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Aryl Hydrocarbon Receptor Deficiency Enhances Insulin Sensitivity and Reduces PPAR-α Pathway Activity in Mice

Background: Numerous man-made pollutants activate the aryl hydrocarbon receptor (AhR) and are risk factors for type 2 diabetes. AhR signaling also affects molecular clock genes to influence glucose metabolism. Objective: We investigated mechanisms by which AhR activation affects glucose metabolism....

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Detalles Bibliográficos
Autores principales: Wang, Chun, Xu, Can-Xin, Krager, Stacey L., Bottum, Kathleen M., Liao, Duan-Fang, Tischkau, Shelley A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261983/
https://www.ncbi.nlm.nih.gov/pubmed/21849270
http://dx.doi.org/10.1289/ehp.1103593