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Aryl Hydrocarbon Receptor Deficiency Enhances Insulin Sensitivity and Reduces PPAR-α Pathway Activity in Mice
Background: Numerous man-made pollutants activate the aryl hydrocarbon receptor (AhR) and are risk factors for type 2 diabetes. AhR signaling also affects molecular clock genes to influence glucose metabolism. Objective: We investigated mechanisms by which AhR activation affects glucose metabolism....
Autores principales: | Wang, Chun, Xu, Can-Xin, Krager, Stacey L., Bottum, Kathleen M., Liao, Duan-Fang, Tischkau, Shelley A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261983/ https://www.ncbi.nlm.nih.gov/pubmed/21849270 http://dx.doi.org/10.1289/ehp.1103593 |
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