A Fluorescence-Based High-Throughput Assay for the Discovery of Exchange Protein Directly Activated by Cyclic AMP (EPAC) Antagonists

BACKGROUND: The discovery, more than ten years ago, of exchange proteins directly activated by cAMP (EPAC) as a new family of intracellular cAMP receptors revolutionized the cAMP signaling research field. Extensive studies have revealed that the cAMP signaling network is much more complex and dynami...

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Detalles Bibliográficos
Autores principales: Tsalkova, Tamara, Mei, Fang C., Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262007/
https://www.ncbi.nlm.nih.gov/pubmed/22276201
http://dx.doi.org/10.1371/journal.pone.0030441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262007/
https://www.ncbi.nlm.nih.gov/pubmed/22276201
http://dx.doi.org/10.1371/journal.pone.0030441

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