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Temporal Expression of Bacterial Proteins Instructs Host CD4 T Cell Expansion and Th17 Development

Pathogens can substantially alter gene expression within an infected host depending on metabolic or virulence requirements in different tissues, however, the effect of these alterations on host immunity are unclear. Here we visualized multiple CD4 T cell responses to temporally expressed proteins in...

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Detalles Bibliográficos
Autores principales: Lee, Seung-Joo, McLachlan, James B., Kurtz, Jonathan R., Fan, Danhua, Winter, Sebastian E., Baumler, Andreas J., Jenkins, Marc K., McSorley, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262010/
https://www.ncbi.nlm.nih.gov/pubmed/22275869
http://dx.doi.org/10.1371/journal.ppat.1002499