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Human-like PB2 627K Influenza Virus Polymerase Activity Is Regulated by Importin-α1 and -α7

Influenza A viruses may cross species barriers and transmit to humans with the potential to cause pandemics. Interplay of human- (PB2 627K) and avian-like (PB2 627E) influenza polymerase complexes with unknown host factors have been postulated to play a key role in interspecies transmission. Here, w...

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Detalles Bibliográficos
Autores principales: Hudjetz, Ben, Gabriel, Gülsah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262014/
https://www.ncbi.nlm.nih.gov/pubmed/22275867
http://dx.doi.org/10.1371/journal.ppat.1002488