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Regulation of MMP-3 expression and secretion by the chemokine eotaxin-1 in human chondrocytes

BACKGROUND: Osteoarthritis (OA) is characterized by the degradation of articular cartilage, marked by the breakdown of matrix proteins. Studies demonstrated the involvement of chemokines in this process, and some may potentially serve as diagnostic markers and therapeutic targets; however, the under...

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Detalles Bibliográficos
Autores principales: Chao, Pin-Zhir, Hsieh, Ming-Shium, Cheng, Chao-Wen, Lin, Yung-Feng, Chen, Chien-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262051/
https://www.ncbi.nlm.nih.gov/pubmed/22114952
http://dx.doi.org/10.1186/1423-0127-18-86