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Disease-Specific Non-Reducing End Carbohydrate Biomarkers for Mucopolysaccharidoses

A significant need exists for improved biomarkers for differential diagnosis, prognosis and monitoring of therapeutic interventions for mucopolysaccharidoses (MPS), inherited metabolic disorders that involve lysosomal storage of glycosaminoglycans. Here, we report a simple reliable method based on t...

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Detalles Bibliográficos
Autores principales: Lawrence, Roger, Brown, Jillian R., Al-Mafraji, Kanar, Lamanna, William C., Beitel, James R., Boons, Geert-Jan, Esko, Jeffrey D., Crawford, Brett E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262053/
https://www.ncbi.nlm.nih.gov/pubmed/22231271
http://dx.doi.org/10.1038/nchembio.766