Small Molecule Proteostasis Regulators for Protein Conformational Diseases

Protein homeostasis (proteostasis) is essential for cellular and organismal health. Stress, aging, and the chronic expression of misfolded proteins, however, challenge the proteostasis machinery and the vitality of the cell. Enhanced expression of molecular chaperones, regulated by heat shock transc...

Descripción completa

Detalles Bibliográficos
Autores principales: Calamini, Barbara, Silva, Maria Catarina, Madoux, Franck, Hutt, Darren M., Khanna, Shilpi, Chalfant, Monica A., Saldanha, Sanjay A., Hodder, Peter, Tait, Bradley D., Garza, Dan, Balch, William E., Morimoto, Richard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262058/
https://www.ncbi.nlm.nih.gov/pubmed/22198733
http://dx.doi.org/10.1038/nchembio.763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262058/
https://www.ncbi.nlm.nih.gov/pubmed/22198733
http://dx.doi.org/10.1038/nchembio.763

Ejemplares similares