Cargando…

Dynamin 2 Mediates PDGFRα-SHP-2-Promoted Glioblastoma Growth and Invasion

Dynamin 2 (Dyn2), a large GTPase, is involved in receptor tyrosine kinase (RTK)-promoted cell migration. However, molecular mechanisms by which Dyn2 regulates RTK-induced cell migration have not been established. Recently we reported that SHP-2 and PI3K mediate PDGFRα-promoted glioma tumor growth an...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, H, Liu, KW, Guo, P, Zhang, P, Cheng, T, McNiven, MA, Johnson, GR, Hu, B, Cheng, SY
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262067/
https://www.ncbi.nlm.nih.gov/pubmed/21996738
http://dx.doi.org/10.1038/onc.2011.436