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Timing Facilitated Site Transfer of an Enzyme on DNA

Many enzymes that react with specific sites in DNA exhibit the property of facilitated diffusion, where the DNA chain is used as a conduit to accelerate site location. Despite the importance of such mechanisms in gene regulation and DNA repair, there have been few viable approaches to elucidate the...

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Detalles Bibliográficos
Autores principales: Schonhoft, Joseph D., Stivers, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262087/
https://www.ncbi.nlm.nih.gov/pubmed/22231272
http://dx.doi.org/10.1038/nchembio.764