RNase H and Postreplication Repair Protect Cells from Ribonucleotides Incorporated in DNA

The chemical identity and integrity of the genome is challenged by the incorporation of ribonucleoside triphosphates (rNTPs) in place of deoxyribonucleoside triphosphates (dNTPs) during replication. Misincorporation is limited by the selectivity of DNA replicases. We show that accumulation of ribonu...

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Detalles Bibliográficos
Autores principales: Lazzaro, Federico, Novarina, Daniele, Amara, Flavio, Watt, Danielle L., Stone, Jana E., Costanzo, Vincenzo, Burgers, Peter M., Kunkel, Thomas A., Plevani, Paolo, Muzi-Falconi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262129/
https://www.ncbi.nlm.nih.gov/pubmed/22244334
http://dx.doi.org/10.1016/j.molcel.2011.12.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262129/
https://www.ncbi.nlm.nih.gov/pubmed/22244334
http://dx.doi.org/10.1016/j.molcel.2011.12.019

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