The PI3K/Akt pathway mediates the expression of type I collagen induced by TGF-β2 in human retinal pigment epithelial cells

PURPOSE: Transforming growth factor (TGF)-β is a key mediator of proliferative vitreoretinopathy, but the cellular mechanisms by which TGF-β induces extracellular matrix protein (ECM) synthesis are not fully understood. This study examined whether the PI3K/Akt pathway is involved in TGF-β2-induced c...

Descripción completa

Detalles Bibliográficos
Autores principales: Yokoyama, Katsuhiko, Kimoto, Kenichi, Itoh, Yuji, Nakatsuka, Kazuo, Matsuo, Noritaka, Yoshioka, Hidekatsu, Kubota, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262137/
https://www.ncbi.nlm.nih.gov/pubmed/21858467
http://dx.doi.org/10.1007/s00417-011-1766-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262137/
https://www.ncbi.nlm.nih.gov/pubmed/21858467
http://dx.doi.org/10.1007/s00417-011-1766-x

Ejemplares similares