LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice

LKB1 is a ‘master’ protein kinase implicated in the regulation of metabolism, cell proliferation, cell polarity and tumorigenesis. However, the long-term role of LKB1 in hepatic function is unknown. In the present study, it is shown that hepatic LKB1 plays a key role in liver cellular architecture a...

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Detalles Bibliográficos
Autores principales: Woods, Angela, Heslegrave, Amanda J., Muckett, Phillip J., Levene, Adam P., Clements, Melanie, Mobberley, Margaret, Ryder, Timothy A., Abu-Hayyeh, Shadi, Williamson, Catherine, Goldin, Robert D., Ashworth, Alan, Withers, Dominic J., Carling, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262187/
https://www.ncbi.nlm.nih.gov/pubmed/21118154
http://dx.doi.org/10.1042/BJ20101721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262187/
https://www.ncbi.nlm.nih.gov/pubmed/21118154
http://dx.doi.org/10.1042/BJ20101721

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