Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer

STAT5 consists of two proteins, STAT5A/B, that impact mammary cell differentiation, proliferation, and survival. In normal development, STAT5 expression and activity are regulated by prolactin signaling with JAK2/ELF5, EGF signaling networks that include c-Src, and growth hormone, insulin growth fac...

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Detalles Bibliográficos
Autores principales: Furth, Priscilla A, Nakles, Rebecca E, Millman, Sarah, Diaz-Cruz, Edgar S, Cabrera, M Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262193/
https://www.ncbi.nlm.nih.gov/pubmed/22018398
http://dx.doi.org/10.1186/bcr2921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262193/
https://www.ncbi.nlm.nih.gov/pubmed/22018398
http://dx.doi.org/10.1186/bcr2921

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