Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL

INTRODUCTION: It is postulated that breast cancer stem cells (bCSCs) mediate disease recurrence and drive formation of distant metastases - the principal cause of mortality in breast cancer patients. Therapeutic targeting of bCSCs, however, is hampered by their heterogeneity and resistance to existi...

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Detalles Bibliográficos
Autores principales: Piggott, Luke, Omidvar, Nader, Pérez, Salvador Martí, Eberl, Matthias, Clarkson, Richard WE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262200/
https://www.ncbi.nlm.nih.gov/pubmed/21914219
http://dx.doi.org/10.1186/bcr2945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262200/
https://www.ncbi.nlm.nih.gov/pubmed/21914219
http://dx.doi.org/10.1186/bcr2945

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