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The chemokine receptor CX(3)CR1 is directly involved in the arrest of breast cancer cells to the skeleton

INTRODUCTION: Skeletal metastases from breast adenocarcinoma are responsible for most of the morbidity and mortality associated with this tumor and represent a significant and unmet need for therapy. The arrival of circulating cancer cells to the skeleton depends first on the adhesive interactions w...

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Detalles Bibliográficos
Autores principales: Jamieson-Gladney, Whitney L, Zhang, Yun, Fong, Alan M, Meucci, Olimpia, Fatatis, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262203/
https://www.ncbi.nlm.nih.gov/pubmed/21933397
http://dx.doi.org/10.1186/bcr3016