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Hsp27 participates in the maintenance of breast cancer stem cells through regulation of epithelial-mesenchymal transition and nuclear factor-κB

INTRODUCTION: Heat shock proteins (HSPs) are normally induced under environmental stress to serve as chaperones for maintenance of correct protein folding but they are often overexpressed in many cancers, including breast cancer. The expression of Hsp27, an ATP-independent small HSP, is associated w...

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Detalles Bibliográficos
Autores principales: Wei, Li, Liu, Tsung-Ta, Wang, Hsiu-Huan, Hong, Hui-Mei, Yu, Alice L, Feng, Hsiang-Pu, Chang, Wen-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262214/
https://www.ncbi.nlm.nih.gov/pubmed/22023707
http://dx.doi.org/10.1186/bcr3042