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Pleurocidin-family cationic antimicrobial peptides are cytolytic for breast carcinoma cells and prevent growth of tumor xenografts

INTRODUCTION: Cationic antimicrobial peptides (CAPs) defend against microbial pathogens; however, certain CAPs also exhibit anticancer activity. The purpose of this investigation was to determine the effect of the pleurocidin-family CAPs, NRC-03 and NRC-07, on breast cancer cells. METHODS: MTT (3-(4...

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Detalles Bibliográficos
Autores principales: Hilchie, Ashley L, Doucette, Carolyn D, Pinto, Devanand M, Patrzykat, Aleksander, Douglas, Susan, Hoskin, David W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262215/
https://www.ncbi.nlm.nih.gov/pubmed/22023734
http://dx.doi.org/10.1186/bcr3043