RAS Mutations and Oncogenesis: Not all RAS Mutations are Created Equally

Mutation in RAS proteins is one of the most common genetic alterations observed in human and experimentally induced rodent cancers. In vivo, oncogenic mutations have been shown to occur at exons 12, 13, and 61, resulting in any 1 of 19 possible point mutations in a given tumor for a specific RAS iso...

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Detalles Bibliográficos
Autores principales: Miller, Mark Steven, Miller, Lance D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262225/
https://www.ncbi.nlm.nih.gov/pubmed/22303394
http://dx.doi.org/10.3389/fgene.2011.00100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262225/
https://www.ncbi.nlm.nih.gov/pubmed/22303394
http://dx.doi.org/10.3389/fgene.2011.00100

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