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RAS Mutations and Oncogenesis: Not all RAS Mutations are Created Equally
Mutation in RAS proteins is one of the most common genetic alterations observed in human and experimentally induced rodent cancers. In vivo, oncogenic mutations have been shown to occur at exons 12, 13, and 61, resulting in any 1 of 19 possible point mutations in a given tumor for a specific RAS iso...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262225/ https://www.ncbi.nlm.nih.gov/pubmed/22303394 http://dx.doi.org/10.3389/fgene.2011.00100 |